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International Animal Research Regulations:

Impact on Neuroscience Research: Workshop Summary

Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.

Impact on Neuroscience Research: Workshop Summary National Research
Council, Institute of Medicine, Division on Earth and Life Studies, Institute for
Laboratory Animal Research, Policy and Global Affairs, Committee on Science,
Technology, and Law, Board on Health Sciences Policy, Forum on Neuroscience
and Nervous System Disorders Bruce M. Altevogt, Anne-Marie Mazza, Theresa M
. Wizemann, Diana E. Pankevich. Costs Bureaucracy in regulatory systems is a
challenge ...

The Role of Purchasers and Payers in the Clinical Research Enterprise

Workshop Summary

In a workshop organized by the Clinical Research roundtable, representatives from purchaser organizations (employers), payer organizations (health plans and insurance companies), and other stakeholder organizations (voluntary health associations, clinical researchers, research organizations, and the technology community) came together to explore: What do purchasers and payers need from the Clinical Research Enterprise? How have current efforts in clinical research met their needs? What are purchasers, payers, and other stakeholders willing to contribute to the enterprise? This book documents these discussions and summarizes what employers and insurers need from and are willing to contribute to clinical research from both a business and a national health care perspective.

11:15 Clinical Research Roundtable Discussion 12:00 Questions and Comments
from the Audience 12:15 pm Lunch (for members and guests in the meeting room
) 1:15 Stakeholder Perspective Please respond to the issues raised in the first ...

Hearing Loss Research at NIOSH:

Reviews of Research Programs of the National Institute for Occupational Safety and Health

The National Institute for Occupational Safety and Health (NIOSH) was established by the Occupational Safety and Health Act of 1970 (U.S. Congress, 1970). Today the agency is part of the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services. NIOSH is charged with the responsibility to "conduct . . . research, experiments, and demonstrations relating to occupational safety and health" and to develop "innovative methods, techniques, and approaches for dealing with [those] problems" (U.S. Congress, 1970). Its research targets include identifying criteria for use in setting worker exposure standards and exploring new problems that may arise in the workplace. Prevention of occupational hearing loss has been part of the NIOSH research portfolio from the time the agency was established. A principal cause of occupational hearing loss is the cumulative effect of years of exposure to hazardous noise. Exposure to certain chemicals with or without concomitant noise exposure may also contribute to occupational hearing loss. Hearing loss may impede communication in the workplace and contribute to safety hazards. Occupationally acquired hearing loss may also have an adverse effect on workers' lives beyond the workplace. No medical means are currently available to prevent or reverse it, although hearing aids are widely used and research on other treatments is ongoing. Occupational hearing loss is a serious concern, although the number of workers affected is uncertain. In September 2004, NIOSH requested that the National Academies conduct reviews of as many as 15 NIOSH programs with respect to the impact and relevance of their work in reducing workplace injury and illness and to identify future directions that their work might take. The Hearing Loss Research Program was selected by NIOSH as one of the first two programs to be reviewed. Hearing Loss Research at NIOSH examines the following issues for the Hearing Loss Research Program: (1) Progress in reducing workplace illness and injuries through occupational safety and health research, assessed on the basis of an analysis of relevant data about workplace illnesses and injuries and an evaluation of the effect that NIOSH research has had in reducing illness and injuries, (2) Progress in targeting new research to the areas of occupational safety and health most relevant to future improvements in workplace protection, and (3) Significant emerging research areas that appear especially important in terms of their relevance to the mission of NIOSH.

... Total number of major recommendations For each: Complete citation (article,
report, or conference where recommendation was made) Summary in one to four
sentences Percentage of target audience that has adopted recommendation 1, 5,
 ...