Sebanyak 725 item atau buku ditemukan

A Meta-analysis of the Effectiveness of Achieving Higher Order Learning Tasks in Cooperative Learning Compared with Competitive Learning

In Silico Analysis and Modeling of Deleterious Single Nucleotide Polymorphism (SNPs) in Human GATA4 Gene

Research Paper from the year 2016 in the subject Medicine - Human Genetics, , language: English, abstract: Congenital heart disease (CHD) is an abnormality in the structure and function of the heart and great vessels caused by embryonic development disorders, it is highly complex and is not fully understood yet. This study performs a computational analysis of the nsSNPs in the GATA4 gene, to identify the possible mutations and propose a modeled structure for the mutant protein that potentially affects its function. The nsSNPs were analyzed using 5 prediction tools: SIFT, Polyphen-2, I-Mutant 3.0, PhD-SNP and Project Hope. The SNPs on 3’UTR and 5’UTR regions were analyzed using PolymRTS and SNP Function Prediction softwares, respectively. Twenty nine nsSNPs were found to be deleterious and damaging by SIFT and 22 nsSNPs by PolyPhen server; 22 nsSNPs were found to be common in both SIFT and PolyPhen server. Also, 6 nsSNPs were observed to be highly deleterious and damaging as per SIFT and PolyPhen server. Moreover, the PolymiRTS results showed 34 SNPs in the 3’UTR region and only one SNP in 5’ UTR by SNP Function Prediction to be functionally significant. Hence, we hope our results will provide useful information that needed to help researchers to do further study in heart disease in children especially in our country

Research Paper from the year 2016 in the subject Medicine - Human Genetics, , language: English, abstract: Congenital heart disease (CHD) is an abnormality in the structure and function of the heart and great vessels caused by embryonic ...

An Analysis and Comparison of Two Essential Oils Extraction Methodologies for Lemongrass (Cymbopogon Citratus (DC.) Stapf)

Lemongrass from te species of citratus have been used in this research in order to anaylze and compare two extraction methodolgy for extracting essential oils from lemongrass. The two methods involved were steam distillation and maceration extraction. Control methods involved were steam distillation and maceration extraction. Control method for this research was steam distillation. There are three types of essential oils were produced by these two methods, which produced from air dried lemongrass leaves, direct heating lemongrass by using drying oven with temperature of 60c and essential oils from fresh lemongrass leaves.

Lemongrass from te species of citratus have been used in this research in order to anaylze and compare two extraction methodolgy for extracting essential oils from lemongrass.