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A Pair of Idols ...

... taken in conjunction with his pink, cleanshaven countenance, seemed an
absurd anachronism, and he wore a splendid coat of fur and leather.
Nevertheless Jock, depressed by the collapse of his masterpiece, paid small
heed to him.

Fundamentals of Nuclear Reactor Physics

Fundamentals of Nuclear Reactor Physics offers a one-semester treatment of the essentials of how the fission nuclear reactor works, the various approaches to the design of reactors, and their safe and efficient operation . It provides a clear, general overview of atomic physics from the standpoint of reactor functionality and design, including the sequence of fission reactions and their energy release. It provides in-depth discussion of neutron reactions, including neutron kinetics and the neutron energy spectrum, as well as neutron spatial distribution. It includes ample worked-out examples and over 100 end-of-chapter problems. Engineering students will find this applications-oriented approach, with many worked-out examples, more accessible and more meaningful as they aspire to become future nuclear engineers. A clear, general overview of atomic physics from the standpoint of reactor functionality and design, including the sequence of fission reactions and their energy release In-depth discussion of neutron reactions, including neutron kinetics and the neutron energy spectrum, as well as neutron spatial distribution Ample worked-out examples and over 100 end-of-chapter problems Full Solutions Manual

Fundamentals of Nuclear Reactor Physics offers a one-semester treatment of the essentials of how the fission nuclear reactor works, the various approaches to the design of reactors, and their safe and efficient operation .

Anti-cancer Activity of Triterpenoids Isolated from Luvunga Scandens Against MCF-7 Cells

Luvunga scandens belong to the family of Rutaceae which usually inhabits tropical and moist environment. This plant is known as 'Mengkurat Jakun' among locals and used traditionally to treat fever and fatigue via decoction. The study aimed to elucidate the compounds from L. scandens stem, which were isolated using bioactivity guided isolation together with their mechanism of action on human breast cancer cell (MCF-7). The bioactivity-guided isolation of cytotoxic agent of the stem of L. scandens resulted in the isolation and characterization of a new triterpenoid from this species, 3-oxotirucalla-7,24-dien-21-oic-acid (2), along with a known triterpenoid, flindissol (1). The isolation was conducted using chromatographic techniques on silica gel and sephadex LH-20. The structures of the isolated compounds were elucidated on the basis of spectroscopic analysis including UV, IR, NMR, MS and 2D NMR. The cytotoxic activity of the plant on the proliferation of MCF-7 cell line was evaluated by MTT, WST-1 assay, scanning electron microscope (SEM), flow cytometry and RT-qPCR. The cytotoxic evaluation of the extracts showed that IC50 value of the dichloromethane (LSC-SD) and methanol (LSC-SM) extracts from the stem were 75.0 and 77.0 μg/mL respectively. Whereas IC50 value of n-hexane (LSF-H), n-hexane:DCM (LSF-HD), DCM (LSF-D) and DCM:MeOH (LSF-DM) fraction extracts were 97.5, 35, 98.9 and 94 μg/mL respectively. The IC50 value of MeOH (LSF-M) fraction could not be extrapolated since none of the concentration of this extract was able to reduce the proliferation activity to 50 %. Compound 1 and 2 showed potent cytotoxicity against MCF-7 cell line with IC50 values of 13.8 μM and 27.5 respectively after 24 h of treatment. Doxorubicin was used as a positive control drug with IC50 values of 6.21 μM. Morphological analysis of the cells surface exhibit the apoptosis results after 24 h treated with LSC-SD extract, 1 and 2, where the cells were rounded up, shrank and lost contact with neighboring cells. Apoptosis of MCF-7 cells treated with both compounds were confirmed by flow cytometry. The results show that compound 1 and 2 exert their anti-proliferative effect on MCF-7 cells through inhibiting cell cycle where the distribution of cells at Sub G1 phase was 7.7 and 9.3 % respectively. Further evident of apoptosis induction by compound 1 and 2 towards MCF-7 cell lines were assayed by RT-qPCR on the expression of PUMA, caspase-8 and caspase-9. In this assay, both compounds showed the increased of the expression of PUMA, caspase-8 and caspase-9 gene. In conclusion, both triterpenoids, 3-oxotirucalla-7,24-dien-21-oic-acid (2) and flindissol (1) have a potential to be developed as anticancer agents against breast cancer.

Luvunga scandens belong to the family of Rutaceae which usually inhabits tropical and moist environment.

Koperasi meningkatkan kemandirian usaha kecil menengah dan KUD

reformasi bidang ekonomi

Collection of regulations with reference to cooperative societies, Indonesia.

Collection of regulations with reference to cooperative societies, Indonesia.

Giving Meaning to Economic, Social, and Cultural Rights

The Universal Declaration of Human Rights, arguably the founding document of the human rights movement, fully embraces economic, social, and cultural rights, as well as civil and political rights, within its text. However, for most of the fifty years since the Declaration was adopted by the General Assembly of the United Nations, the focus of the international community has been on civil and political rights. This focus has slowly shifted over the past two decades. Recent international human rights treaties—such as the Convention on the Rights of the Child and the Convention on the Elimination of All Forms of Discrimination Against Women—grant equal importance to protecting and advancing nonpolitical rights. In this collection of essays, Isfahan Merali, Valerie Oosterveld, and a team of human rights scholars and activists call for the reintegration of economic, social, and cultural rights into the human rights agenda. The essays are divided into three sections. First the contributors examine traditional conceptualizations of human rights that made their categorization possible and suggest a more holistic rights framework that would dissolve such boundaries. In the second section they discuss how an integrated approach actually produces a more meaningful analysis of individual economic, social, and cultural rights. Finally, the contributors consider how these rights can be monitored and enforced, identifying ways international human rights agencies, NGOs, and states can promote them in the twenty-first century.

This book was inspired by a conference celebrating the tenth anniversary of the
International Human Rights Programme at the Faculty of Law, University of
Toronto. The 1998 conference, entitled ''Linking the Domestic and the
International: ...

Politik Syariat Islam

dari Indonesia hingga Nigeria

Issues on implementation of Islamic law in several countries.

Dengan kata lain, formalisasi itu bukan konstitusionalisme. Jika diingat bahwa
konstitusionalisme adalah masalah pokok di negeri-negeri Muslim yang dibahas
dalam bab-bab terdahulu, maka formalisasi sanksi terhadap pelanggaran
perintah dan larangan agama menjadi persoalan tambahan dalam kaitan antara
hukum dan kekuasaan. Dengan latar belakang uraian di atas, maka perlu sekali
dipertimbangkan kembali nilai dan arti penting perintah dan larangan agama
yang ...